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These findings position GLP-1RAs as a potential fourth pillar of kidney-protective therapy in diabetes, alongside renin-angiotensin system inhibitors (RASi), SGLT2i, and finerenone, and suggest a shift toward rapid initiation of combination therapies for maximum kidney protection

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Overexpression of GGT1 (GGT1 + ) in cells 40 resulted in increased GGT1 protein levels (Fig

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Abbott NJ, Patabendige AA, Dolman DE, Yusof SR, Begley DJ

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NTvG 2002;146: 459-64 5

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