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Wai SG, Rozance PJ, Wesolowski SR, Hay WW Jr, Brown LD

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Fold change values were normalized (within all samples in each group) ranging from 0 to 1 and further rescaled to make the sum of the normalized fold change as one

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By combining the actions of both GLP-1 and GIP, Tirzepatide enhances insulin secretion and reduces glucagon release