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Acetylcysteine for prevention of renal outcomes in patients undergoing coronary and peripheral vascular angiography: main results from the randomized Acetylcysteine for Contrast-induced nephropathy Trial (ACT)

A 2020 review of case reports found that self-administered coffee enemas caused adverse effects such as: abdominal pain bloody stool rectal pain or burning proctocolitis, or inflammation of the rectal lining colitis, or inflammation of the colon The review also noted three deaths following coffee enema

2015;308:F981992

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Glutathione trisulfide Glutathione trisulfide (GSSSG) is a potent neuroprotective agent with anti-inflammatory activity

Critically, sophisticated EEG analysis confirmed no sedation in the classical pharmacological sense establishing that DSIP sustains natural sleep functions rather than inducing pharmacological sedation