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FDA approves Novo Nordisk's oral semaglutide for cardiovascular (CV) risk reduction in adults with type 2 diabetes who are at high risk, including those who have not had a prior CV event
Endothelial IR is present in diabetic patients with endothelial dysfunction, which disrupts endothelial insulin signalling through the activation of PKC- and NF-B activity [80]
Constipation is reported less frequently than nausea or diarrhoea in clinical trials, nevertheless it remains a significant and sometimes persistent concern in real-world use
San Antonio, TX (1993)
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