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Factors Influencing the Effectiveness of Vitamin B12 Shots Several factors can influence how quickly and effectively a Vitamin B12 shot works: Severity of Deficiency : Individuals with severe Vitamin B12 deficiency may experience a more noticeable and rapid improvement in symptoms compared to those with mild deficiency
If you have tried oral B12 before and felt no change, this may be part of the reason, and it is worth mentioning to your provider
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