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Subcutaneous administration of vitamin B12 is sometimes employed, especially in patients with congenital cobalamin metabolism disorders who require high doses to maintain normal metabolic pathways

In children aged 5 through 17 years, the most common (10%) solicited local adverse reactions were pain (56%), redness (18%), and swelling (14%), and the most common systemic adverse reactions were muscle aches (29%), fatigue (20%), and headache (15%)

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When the number of platelets is low, one may complain of prolonged bleeding from cuts, bleeding gums or nose, blood in urine or stool, abnormally heavy menstrual periods in women, fatigue and general weakness