High levels of the transcription factor NRF2 can induce metabolic reprogramming in dormant tumor cells, re-establishing redox homeostasis and de novo synthesis of nucleotides, accelerating the activation of tumor cells and tumor recurrence
Most patients administer injections five days per week
Zivanovic A, Miller JT, Munro SA, Knutson TP, Li Y, Passow CN, et al
doi: 10.1161/jaha.122.026728 95 EkhzaimyAAMasoodABenabdelkamelHElhassanTMusambilMAlfaddaAA
228,229 For instance, GLP-1 RAs facilitate the regeneration of pancreatic -cells, contributing to tissue restoration
The balance between efficacy and tolerability is therefore critical