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Retatrutide still has no MHRA or FDA approval these are trial results, and in the UK it remains a research compound for laboratory use only
They are not reviewed or approved by the FDA for safety or effectiveness and may be prescribed when FDA-approved alternatives are unavailable or unsuitable
In this letter, we summarise the findings of the most recent studies that have reported the potential impact of GLP-1RAs on the residual gastric content (RGC), in light of an increased risk of aspiration pneumonia for patients undergoing general anaesthesia and/or deep sedation (Table 1)
Sometimes the answer is not push through it. The answer may be to slow the titration, adjust the dose, treat constipation, improve hydration, change eating patterns, or pause and reassess
Author contributions AR: Conceptualization, Writing original draft, Formal analysis, Investigation, Methodology, Writing review & editing