Peptide bioregulators: The new class of geroprotectors
Final Thoughts GHK-Cu represents one of the more scientifically grounded options within the peptide therapy space not a trend built on empty promises, but a compound with decades of research behind its role in tissue repair and skin renewal
Most of these are phages and prey on our gut microbes without affecting us directly (Cryan et al., 2019) but they nonetheless have been reported to affect their hosts gut-blood barrier (Fitzgerald et al., 2019)
GCL belongs to the class of proteins that are sensitive to oxidative stress, and its expression is mainly under the regulation of the Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2), a transcription factor that regulates a wide array of antioxidant responsive element-driven genes in various cell types ( the novo GSH biosynthesis is glutathione synthase (GS)
Glutathione is like a cleanup crew, helping protect the same cells and detoxify your liver
It also enhances the activity of detoxification enzymes, such as glutathione S-transferases (GSTs), which conjugate toxins to Glutathione, facilitating their elimination (Lu, 2013)