Muscle doesnt return as quickly as fat does, and losing it can affect strength, mobility, and long-term metabolic health
But GLP-1 agonist medications arent a forever fix
Each injection produces an independent GH secretory episode, preserving the pulsatile pattern that maintains GH receptor sensitivity
Since reduced anti-coagulant properties and increased pro-inflammatory mediators and reactive oxygen species play important roles in the development of both endothelial dysfunction and atherosclerosis, the association between the two is almost ubiquitous [88]
If lying down consistently makes the headache worse (or better), and standing does the opposite, you're dealing with a CSF pressure issue, not migraine or medication overuse
But the American Society of Anesthesiologists (ASA) urges caution: "The potential benefit of withholding GLP-1s around surgery must be balanced against the risks." Why