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A 2025 systematic review and meta-analysis of 38 randomised controlled trials in women with DOR found that DHEA, testosterone, high-dose gonadotropins, and delayed-start protocols all improved the number of oocytes retrieved during IVF stimulation
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Results build progressively, with significant improvements typically seen after 1216 weeks
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Specifically, they observed that elevated oxidative stress, indicated by markers like malondialdehyde and myeloperoxidase, played a significant role in contributing to the symptoms of long COVID
