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Un porcentaje significativo de pacientes recupera parte del peso perdido en los meses siguientes, especialmente si no se consolidaron cambios en el estilo de vida y si durante el tratamiento no hubo ejercicio fsico, resultando en prdida de grasa y masa muscular

This is best achieved with either multiple dose injection of subcutaneous basal insulin analogues and mealtime rapid-acting or ultra-rapid-acting insulin analogues, or with continuous subcutaneous insulin infusion of a rapid-acting insulin analogue via a pump, delivered as continuous basal insulin combined with manual mealtime boluses

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J Agric Food Chem (2017) 65(13):271929