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So far, three major problems have kept GLP-1 drugs injectable rather than oral: enzymatic degradation, poor bioavailability, and the sheer cost of manufacturing
Phen-Fen also evoked modest weight loss but caused the deaths of hundreds of people, with exact numbers still unknown
Impossible to replicate: you cannot recreate conditions or compare against other studies because the internal composition is unknown
They are sensitive to hydration status and can give misleading readings
That is developing science, not a recommendation: which molecule fits your case is a decision a licensed clinician makes
The decline after week 24 does not mean heart rate returns completely to baseline while on treatment
