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Richard DiMarchi, one of the pioneers of GLP-1 drugs, argues that the degree which they have helped to manage excess body weight compares with the historic breakthroughs in the management of excess blood pressure, excess lipids and excess glucose

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Bennett WL, Maruthur NM, Singh S, Segal JB, Wilson LM, Chatterjee R, et al

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Individuals also tend to lose about of a quarter of their weight in lean muscle mass due to reduced food intake from gastrointestinal distress, lack of appetite, or a combination of the two

Should patients on GLP-1 drugs have lab work monitored