10.1016/j.yexcr.2020.112056 55 MilteR.CrottyM
When GLP-1 binds to specific receptors in the body, it triggers a series of mechanisms that regulate blood sugar levels, slow the movement of food through the digestive system and act on neurons in the brainall of which give people a feeling of fullness that helps them eat less and lose weight
While many media reports tout the remarkable effectiveness of GLP-1 drugs (and their great expense) for weight loss, few address the serious side effects associated with their use, such as loss of skeletal muscle (and the risk of sarcopenia) and bone mineral density (and the risk of osteomalacia and osteoporosis), and the weight gain that typically follows their discontinuation
J Nutr 137:812S818S
The male and female steady states
Instead, work with a qualified medical professional who can recommend science-backed medications, along with sustainable diet, exercise, sleep and stress management practices for lasting metabolic health