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69 Conversely, the extracellular release of decorin (DCN, an extracellular matrix-derived damage-associated signaling proteoglycan), 70 high mobility group box 1 (HMGB1, an architectural DNA-binding factor in the cell nucleus), 71 and nuclear receptor coactivator 4 (NCOA4, a mediator of ferritinophagy) 72,73 may function as damage-associated alarm signals that promote inflammatory responses in the local microenvironment
The most frequently reported adverse events with liraglutide were mild or moderate nausea and diarrhea, both of which were transitory [16]
Furthermore, pro-inflammatory and pro-fibrotic cytokines, including activin A, visfatin, transforming growth factor-1 (TGF-1), and MCP-1, promote fibroblast proliferation and myofibroblast activation, resulting in atrial and ventricular arrhythmias (103)
Eur J Pharmacol 982: 176936
Apolipoprotein B-48: a unique marker of chylomicron metabolism
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