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(Thng 5-6 nm 2016)

Patients experience the benefits of increased energy and improved nerve functioning

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Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

Compound 3 was isolated by silica gel column chromatography using a dichloromethane/methanol (DCM:MeOH = 40:1, V/V) eluent (yield: 75%)