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Constipation is often most pronounced during dose escalation phases and may improve with continued therapy as the body adapts

A plausible mechanism does not establish an effective ratio, compatibility, long-term safety or a clinically meaningful result

In the Reepithelization stage, BV triggers human epidermal keratinocyte division and migration while decreasing interleukin-8 (IL-8) and Tumor necrosis factor- (TNF-)

Higher doses increase appetite suppression but also increase the likelihood of nausea and other digestive issues

Maintaining adequate hydration is crucial, particularly during the initial treatment phase when gastrointestinal side effects are most pronounced