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Chronic hyperglycemia results in the accumulation of advanced glycation end products (AGEs), which is higher in diabetic patients than in normal patients 14

Berberine and other ingredients could accumulate to higher levels in people with reduced kidney function

Samples were loaded on a nanoscale capillary reverse-phase C18 column by an HPLC system (Thermo Fisher Scientific Ultimate 3000) and eluted by a gradient (90 min)

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To stay hydrated, aim to drink 91125 fluid ounces daily if experiencing these side effects