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Drug monitoring is recommended as neurotoxicity is dependent on serum concentration, which can result in mild nystagmus, tremors and nausea or at higher levels produce coma and seizures

These findings highlight the importance of maintaining continuous GLP-1 treatment to sustain cardiovascular benefits and indicate that strategies to reduce treatment discontinuity should be developed to maximize the cardioprotective effects of GLP-1s

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Conclusion Switching from tirzepatide to semaglutide can be complex, yet it is an increasingly relevant clinical scenario

doi: 10.1042/CS20060103 95 Berlanga-AcostaJCibrianDValiente-MustelierJSurez-AlbaJGarca-OjalvoAFalcn-CamaVet al

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