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The idea is that these ingredients promote short-chain fatty acid production, particularly butyrate, which then stimulates additional GLP-1 secretion from the colon
AgeMD dosage suggestion: Lowest Beneficial Dose approach (5 mg/mL) AgeMD providers follow a Lowest Beneficial Dose protocol gradual titration to find the dose effective for your individual biology, not the maximum tolerated level
Sies H, Sharov VS, Klotz LO, Briviba K
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An ongoing phase 2 trial testing NO 2 -OA in obese asthmatics (NCT03762395) is revealing patient safety and insight into the gene expression, metabolomic, inflammatory signaling, and physiological responses that small molecule nitroalkene induces in obese subjects
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