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** In soggetti con funzione renale fortemente compromessa o in dialisi, la somministrazione orale cronica di L,carnitina pu, dare luogo ad accumulo di TMA e TMAO nel sangue con conseguente trimetilamminuria, condizione patologica caratterizzata da un forte &quot,odore di pesce&quot, presente nelle urine, nell,alito e nel sudore del paziente (vedi paragrafo 5.2) *** In pazienti uremici sono stati segnalati lievi sintomi miastenici **** Reazioni in sede di iniezione sono state segnalate soltanto nella somministrazione i.v

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Nat Commun 16(1):7233 Yang L, Lin Z, Mu R, Wu W, Zhi H, Liu X et al (2024) Neurons enhance bloodbrain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion

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The drug is still working

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In addition, glutathione has been shown to be a significant factor in the excretion of heavy metals such as mercury, cadmium and arsenic

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If "mitochondrial signaling in aging" is the framing, MOTS-c is the literature favorite

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Mashayekhi F, Mirzajani E, Naji M, Azari M

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