FIGURE 1 Fecal Sample Collection and Analyses A fresh fecal sample (within 15 min of defecation) per cat was collected on d 0, d 35, and d 65 for microbiota, short-chain fatty acids (SCFAs), and metabolome analysis
It's crazy what can be done with new technology
NK Cell Cytotoxicity Impairment Natural Killer cells provide first-line immune surveillance without prior antigen sensitisation, making their function critical in immune defence against diabetes
Losing weight also plays a big role
They compared patients who continued receiving GLP-1 monotherapy with those who received add-on bupropion/naltrexone (combination therapy)
Recent advancements in sustained-release formulations, like PLGA nanoparticles for delivering exendin-4, show promise in preclinical models but still require validation in human studies (Wang et al., 2023)