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While the consistency of the association across comparator therapies and the scale of the dataset support the signals clinical relevance, biological plausibility remains hypothesis-generating and is based on investigator interpretation rather than validated mechanistic evidence

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Michael Perelman introduced the concept of the sexual tipping point, which looks at the interaction of excitatory and inhibitory biomedical, psychological, and cultural factors to determine sexual response

doi: 10.1016/j.conctc.2022.100944 65

Reusing the same spot leads to lumps, bruising, and slower absorption