The neurovascular unit uncoupling initiates glial activation, neuronal apoptosis, blood-retinal barrier leakage, and ischemia, shifting the understanding of DR from a solely vascular disorder to a neurovascular one where early NVU impairment predicts functional deficits like reduced contrast sensitivity and progression to vision-threatening complications ( 2.2 Inflammatory pathways Inflammation is a central driver of early-stage diabetic retinopathy (DR), particularly in non-proliferative diabetic retinopathy (NPDR), where it exacerbates vascular damage and compromises the blood-retinal barrier (BRB)
This is why early screening for the autoantibodies that show up before you have any symptoms of T1D is so important, particularly since today there is a medication that can slow the progression to stage 3
degradation reported above 25 C
Gastroenterology , 73:13831387
Garlic and onions also high in sulfur and supportive of liver detox pathways
Store in a cool, dry place away from direct sunlight