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Phentermine's stimulant effects directly contradict tirzepatide's cardiovascular benefits, and no clinical trials support improved weight loss outcomes from combining them
It is also used to treat diseases of nerves in the eyes
What exists is literature discussing why researchers have theorized these pairings might be of interest, not evidence that they produce any specific outcome together
Research models evaluate these pathways by administering precise g doses of B12 and observing biochemical or physiological markers
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