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It also assists in maintaining healthy liver detoxification pathways and cellular protection

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Adjustment strategies relied on measured confounders such as HbA1c and BMI but could not fully account for time-varying confounding by indication

Patients who lost the most weight regained the most in absolute terms

Other possibilities are also plausible, as for instance, IGF-I may influence the peripheral immune reaction, what in turn could reduce CNS inflammation, demyelination, and BBB permeability[82]

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