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In this context, our findings suggest that devising treatment algorithms combining MBS and pharmacotherapy can lead to more effective and patient-centered long-term treatment strategies for severe obesity
However, DPP-4 inhibitors (such as sitagliptin or linagliptin) should be discontinued when initiating semaglutide, as both drug classes work through incretin pathways, and combined use offers no additional glycemic benefit while potentially increasing adverse effects
AMPLITUDE-O Trial Investigators, Gerstein HC, Sattar N, Rosenstock J, Ramasundarahettige C, Pratley R, Lopes RD et al (2021) Cardiovascular and renal outcomes with efpeglenatide in Type 2 diabetes
Weight regain is not a guarantee, but you must keep following a diet and exercise plan, just as you were while taking your medication
Reimbursement policy analysis covering Medicare price negotiation impacts, commercial payer coverage determinations, and international HTA framework evolution influencing market access