glp 1 image GLP-1 Drugs and the Physiology of Metabolic Health Navigating GLP-1 use in therapy

Candidates like Eli Lillys retatrutide and Amgens MariTide are raising the bar, with Phase II trials showing weight loss exceeding 24%, a level comparable to that achieved with bariatric surgery

What does a Vitamin B12 injection feel like

Autopsy results will often find marked fatty liver (hepatic steatosis) and cerebral edema

Eight weeks of aerobic exercise significantly activated the System Xc /GPx4 signaling pathway in the prefrontal cortex of APPswe/PS1dE9 transgenic AD mice, up-regulated FTL and BACE1 expression, significantly downregulated 4-HNE levels, inhibited oxidative stress, lipid peroxidation, and ferroptosis, reduced A positivity, alleviated neuronal morphological abnormalities, and improved learning and memory functions in AD mice (Li et al., 2024a)

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

Endocrine Connections, 14(5), e240529