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Tirzepatide : Sold as Mounjaro, it combines GLP-1 and GIP receptor agonist activity for enhanced efficacy in weight reduction

10.1016/j.bbrc.2011.08.007 Biochem

These drugs have a low risk of hypoglycemia when used alone, but the risk increases if combined with insulin or sulfonylureas

After cell adhesion, the media containing different concentrations of compounds were added and incubated for 24 h

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The radioiodinated form of this molecule, I-NDP-alpha-MSH, is the standard displacement radioligand for the whole receptor family, which is why it appears throughout melanocortin binding literature