Observational and review-level evidence indicates that patients receiving GLP-1RAs may exhibit micronutrient insufficiencies and lean mass reduction, particularly in vulnerable populations or during prolonged therapy [94, 101]
Food And Drug Administration
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It is a functional biomarker that reflects the efficiency of interconnected metabolic pathways and should be considered alongside glutathione status, B vitamin sufficiency and the wider clinical picture
Decreased appetite This is expected on medications that suppress appetite, but the tendency for appetite to normalize while efficacy is maintained over longer term use in most patients