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(5,6) KPV exerts potent anti-inflammatory effects by modulating key intracellular signaling pathways, including the inhibition of NF-B activation, which plays a central role in controlling the transcription of pro-inflammatory genes

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doi: 10.4049/jimmunol.173.6.4066 65 SchwarzerEBellomoGGiribaldiGUlliersDAreseP

The study confirmed that BPC-157s effects on tube formation were mediated via the ERK1/2 signalling pathway, as its effects were significantly inhibited by the ERK1/2 inhibitor PD98059

They might start with lower doses to avoid side effects

Smoday I.M., Petrovic I., Kalogjera L., Vranes H., Zizek H., Krezic I., Gojkovic S., Skorak I., Hriberski K., Brizic I., et al