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Potential mechanisms by which peptide exposure could influence surgical outcomes include dysregulated angiogenesis contributing to hematoma formation, altered inflammatory signaling affecting early wound healing, and perturbations in collagen organization that may influence soft-tissue integrity during the critical postoperative period
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Many compounded formulations include B12 , glycine , or niacinamide to offset this effect and improve tolerability
Animal studies using BPC-157 on transected tendons show restored biomechanical properties approaching pre-injury levels
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