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Safety & Candidacy Most adults qualify with a BMI of 30 or higher , or 27 or higher with a weight-related condition such as high blood pressure, prediabetes or type 2 diabetes, high cholesterol, or sleep apnea
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The trial also reported improvements from baseline in cardiovascular risk factors including total cholesterol, triglycerides, and systolic blood pressure
Medication is a powerful tool to quiet the physical urge to use, but it is not a standalone cure for addiction
Figure 1 The baseline obesity classification fluctuated greatly from 319 to 393 kg/m2
Second, head-to-head comparative trials between GLP-1 RA monotherapy, dual agonists, and triple agonists in MASH populations with histological endpoints are entirely lacking: current selection among agents relies on indirect comparisons across trials with different inclusion criteria and follow-up periods
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