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First, an insulin-secreting -cell line MIN-6 cells stably expressing GLP-1R (GLP-1R-MIN-6 cells) was prepared, as we intended to observe a stronger effect of GLP-1R activation than that of endogenous GLP-1R
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Note the foods you consume, your daily water intake, and any symptoms of constipation
Palmitate, partly a product of hepatic de novo lipogenesis, has a particularly detrimental role in reducing -cell function, most likely by inducing -cell dedifferentiation 50
In pancreatic ductal adenocarcinoma, the KRAS mutation induces reverse electron transport via mitochondrial complex I, generating O 2 that activates the MAPK/ERK pro-proliferative signaling axis [395]