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Over one year, liraglutide did not significantly improve the primary endpoint (change in cerebral glucose metabolic rate in certain brain regions), but secondary endpointsincluding brain volume loss, and cognitive measuresshowed benefit: ~50% less loss in several brain regions compared to placebo
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Expression of glutathione, glutathione peroxidase and glutathione S-transferase pi in canine mammary tumors
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The discovery of GLP-1 and its role in blood sugar regulation and weight loss was more specifically a result of continuing research into gut hormones and their effects on metabolism
Results can vary, and the study participants also received healthy diet and exercise guidance throughout the trial
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