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Toxins 11 (3), 159
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For example, the covalently connected small molecule TLR7/8 agonists of imidazoquinoline to degradable polymer hydrogel nanoparticles with a diameter of 50 nm
These extensive viral protein interactions with host-specific cellular targets could trigger severe human metabolic reprogramming/dysregulation (HMRD), a rewiring of sugar-, amino acid-, lipid-, and nucleotide-metabolism(s), as well as altered or impaired bioenergetics, immune dysfunction, and redox imbalance in the body
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