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The trial has been prospectively registered on australianclinicaltrials.gov.au (ACTRN12620000506998) and will be conducted within the estimand framework for the design and analysis of clinical trials

We recommend the measurement of the Glx/NAA and GABA/Glx ratios, or other ways to normalize for neuronal loss, to both provide neuron specific measurements independent of volume changes as well as reduce methodological uncertainties

Commonly Reported Effects The most frequently mentioned experiences during BPC-157 use include mild injection site reactions such as redness, minor swelling, or temporary discomfort

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These discrepancies may be explained by the hypothesis that L-carnitine supplementation accompanied by high amounts of carbohydrate intake increases skeletal muscle OCTN2 expression through an insulin-mediated mechanism, thereby increasing skeletal muscle carnitine content [28, 29]