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In SURMOUNT-1, adults with obesity (without diabetes) lost an average of 15.0%, 19.5%, and 20.9% of body weight with tirzepatide 5 mg, 10 mg, and 15 mg respectively over 72 weeks, compared to 3.1% with placebo

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Adjustment: After 14 days, the dose was titrated according to the manufacturers guidelines (FDA label) to bring blood testosterone into the normal male range (up to a max of 81 mg/day)

Medication review is prudent, as numerous medications can cause cognitive side effects