Summary of included studies regarding the adverse psychiatric outcomes associated with GLP-1-RAs)
Genetic Pathways and Peptide Response: A Precision Lens Recent research highlights genetic variants in GLP-1 receptor (GLP1R), glucose-dependent insulinotropic peptide receptor (GIPR), fat mass and obesity associated gene (FTO), and melanocortin-4 receptor (MC4R) that may correlate with baseline BMI, weight-loss trajectory, and side-effect tolerability
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The demographic and clinical information of the enrolled patients from TCGA database is presented in Table S1
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This study suggested that Epithalon might have the potential to modify the chromosome regions in the aging cells, activate chromatin, and restore cellular activities that were otherwise suppressed or delayed in geriatric subjects