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FDA Adverse Event Reporting System (FAERS) data from 2022 to 2025 includes 89 reports explicitly mentioning early dosing of tirzepatide

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administration [24]

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Tirzepatide works by: Slowing gastric emptying, which prolongs the time food remains in the stomach Reducing gastrointestinal motility Modulating gut hormone responses Reducing appetite and food intake This delayed gastric emptying is therapeutically beneficial for glycaemic control and weight management, as it promotes satiety and reduces postprandial glucose excursions