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50-52 This finding was further confirmed by the significant improvement in the frailty burden during follow-up among patients with obesity-related HFpEF with semaglutide (vs placebo)
Surveillance data from 2014 to 2024 demonstrated a sustained upward trajectory in NAE reports associated with GLP-1 RAs, peaking in 20232024 (Fig
310 , E947957 (2016)
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10.1080/10715760600722643 98 SwiderskiK.LynchG
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