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Reference: Self-reported side effects of semaglutide and tirzepatide in online communities by Neil K

Similar content being viewed by others Introduction Glucagon-like peptide-1 (GLP-1), an incretin hormone secreted by intestinal enteroendocrine cells, is pivotal for postprandial glucose homeostasis through its modulation of insulin and glucagon secretion, appetite suppression, and gastric emptying [1]

doi: 10.1080/15548627.2025.2481126 42 SnezhkinaAVKudryavtsevaAVKardymonOLSavvateevaMVMelnikovaNVKrasnovGSet al

Not FDA-approved as a blend

Currently, retatrutide is in phase 3 trials that could be released by the end of 2025

blood biomarkers