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Activating cGAS-STING pathway with ROS-responsive nanoparticles delivering a hybrid prodrug for enhanced chemo-immunotherapy

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9 Clinical relevance of RCD pathways Recent clinical data mining utilizing specific RCD-related gene signatures has successfully recapitulated the multifaceted manifestations of RCD in human DKD biopsy samples, highlighting its central role in driving disease progression and immune microenvironment remodeling

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Initially, for both GPX and CAT, a significant upregulation in protein concentrations but not in band number were varied (Fig

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Multiple Scler J 17:289296 Lovell MA, Ehmann WD, Butler SM, Markesbery WR (1995) Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease

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