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Ovulation induction medication Clomiphene and letrozole are the first choice medications used to stimulate ovulation in PCOS patients

Several biological DMARDs have recently emerged including TNF-inhibitor (Amjevita, Renflexis, Erelzi, Cyltezo, Imradl), anti-CD20 antibody (Truxima, Rixathon), IL-6 receptor antibody (Kevzara), RANKL antibody (Pralia), and JAK inhibitor (Olumiant)

doi: 10.3389/fonc.2023.1171794 Received 22 February 2023 Accepted 10 April 2023 Published 10 May 2023 Volume 13 - 2023 Edited by Pina Ziranu, University of Cagliari, Italy Reviewed by Stefano Mariani, University of Cagliari, Italy Updates Copyright 2023 Ebeling, Kowalczyk, Perez-Vazquez and Mattiola

Roos ST, Timmers L, Biesbroek PS, Nijveldt R, Kamp O, van Rossum AC, van Hout GP, Stella PR, Doevendans PA, Knaapen P, et al

Side-Effect Sensitivity Some patients have metabolic profiles that support GLP-1 therapy but struggle to tolerate standard starting doses

Hadi et al