They originate from OPCs (oligodendrocyte progenitor cells), which, when in an advanced stage of maturation, migrate to the periphery of the axonal fibers and, through a combination of epigenetic, translational and environmental cues interconnected through a SOX10 mediation, differentiate into full myelinating oligodendrocytes (89)
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Adherence, persistence, glycaemic control and costs among patients with type 2 diabetes initiating dulaglutide compared with liraglutide or exenatide once weekly at 12-month follow-up in a real-world setting in the United States
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