105,106,107 Notably, not all interactions with ER-resident E3 ubiquitin ligases result in their degradation, exemplified by p62 ubiquitination by RNF26, 108,109 suggesting possible translocation of noncanonical ubiquitinated substrates as a possible mechanism for ERAD recognition
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Clinical and neurochemical effects of acetyl-L-carnitine in Alzheimer's disease Neurobiol Aging 1995
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These practical considerations often prove decisive in real-world decision making