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A patient who begins GLP-1 therapy often experiences significant fatigue, nausea, and reduced appetite in the early weeks
It is important not to take additional doses just because you do not feel immediate relief, as this could lead to an accidental overdose or increased stomach irritation
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It has recently been shown that GLP-1R neurons in the dorsomedial hypothalamic nucleus regulate pancreatic activity by affecting the dorsal motor nucleus of the vagus, specifically lowering blood glucose levels by increasing insulin release (Huang et al., 2022)
Given the Canadian obesity market is already small, the remaining serviceable market is a sliver of a sliver
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