Ive already lost 20 kg
Tirzepatide, known by its brand name Mounjaro, is a once-weekly injection that works by targeting two different receptors in the brain: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 receptor (GLP-1)
Using the same spot repeatedly increases the risk of injection site reactions , skin irritation, and lipodystrophy (changes in fat tissue at the injection site)
Last reviewed: July 1, 2026 Last updated: July 1, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
This supports previous work by researchers at the University of California, Berkeley, and the Children's Hospital Oakland Research Institute led by Professor Bruce Ames
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