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49 Moreover, administration of high doses of IL-1 fails to exacerbate APAP-induced liver injury, further suggesting a limited role of IL-1 signaling in the pathogenesis of APAP hepatotoxicity

It is not a licensed medicine and cannot be sold for human or veterinary consumption

Cancer cachexia is a serious complication that can cause extreme physical weakness in patients, affecting treatment effectiveness and prognosis

This work is supported by the Natural Products & Nanobiotechnology Research Lab, Saveetha Institute of Basic Medical Sciences (SIBMS), Saveetha Institute of Medical and Technical Sciences (SIMATS), (Saveetha University), Thandalam, Chennai, Tamil Nadu 602105, India Conflict of interest The author declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

New delivery methods like GLP-1 patches and new formulations from providers like Evolv GLP-1 , Thrive GLP-1 , and MMIT GLP-1 programs may eventually offer approaches that minimize metabolic shock and, potentially, hair loss risk

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